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A new study (the first clinical trial of its kind) has shown that the GLP-1 agonist semaglutide — known by the brand name Ozempic — may help reduce not only alcohol cravings, but the amount of ...
The Women's Health Initiative (WHI) was a series of clinical studies initiated by the U.S. National Institutes of Health (NIH) in 1991, to address major health issues causing morbidity and mortality in postmenopausal women. It consisted of three clinical trials (CT) and an observational study (OS).
A small clinical trial is the first to show Ozempic can reduce how much alcohol people drink. ... if they were women, or 14 if they were men, within the last month, with two or more heavy drinking ...
CagriSema entered Phase III clinical trials in 2023. [6] In December 2024, Novo Nordisk announced the results of REDEFINE 1, one of their series of Phase III trials, testing weekly cagrilintide 2.4 mg and semaglutide 2.4 mg individually and together versus placebo in obese or overweight subjects with one or more comorbidities. [7]
The authors of the review analyzed the experiences of 6,880 participants in the 116 included randomized clinical trials. All were over the age of 18 and had overweight or obesity.
A prodrug of DNP, HU6, has been tested in clinical trials for weight loss and fatty liver disease. [22] Fibroblast growth factor-21 receptor agonists and drugs increasing FGF-21 activity are being investigated for obesity-related diseases; they can increase energy expenditure and several have been tested in humans. [23] [24]
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