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The mitral valve is also called the bicuspid valve because it contains two leaflets or cusps. The mitral valve gets its name from the resemblance to a bishop 's mitre (a type of hat). It is on the left side of the heart and allows the blood to flow from the left atrium into the left ventricle .
The aortic valve normally has three cusps or leaflets, although in 1–2% of the population it is found to congenitally have two leaflets. [1] The aortic valve is the last structure in the heart the blood travels through before stopping the flow through the systemic circulation. [1]
Mitral stenosis is caused largely by rheumatic heart disease, though is rarely the result of calcification. In some cases, vegetations form on the mitral leaflets as a result of endocarditis, an inflammation of the heart tissue. Mitral stenosis is uncommon and not as age-dependent as other types of valvular disease. [1]
A normal aortic valve is tricuspid. Five types of bicuspid valve are shown, with Type 1 being most prevalent. A bicuspid valve forms when the tissue surrounding one of the cusps (leaflets) of the valve fuses during fetal development. This developmental anomaly can have either a negative or no effect on the individual. Specialty: Cardiology
The aortic valve usually has three leaflets and is located between the left ventricle of the heart, and the aorta. [1] AS typically results in a heart murmur. [1] Its severity can be divided into mild, moderate, severe, and very severe, distinguishable by ultrasound scan of the heart. [1]
The mitral annulus is a fibrous ring that is attached to the mitral valve leaflets. Unlike prosthetic valves, it is not continuous. The mitral annulus is saddle shaped and changes in shape throughout the cardiac cycle. [11] The annulus contracts and reduces its surface area during systole to help provide complete closure of the leaflets.
Valve interstitial cells (VIC), cardiac valve interstitial cells, or also known as valvular interstitial cells (VICs), are the most prevalent cells in the heart valve leaflets, which are a type of mesenchymal stem cells (MSCs) and are responsible for maintaining the extracellular matrix that provides the mechanical properties of the heart valve.
Mitral valve prolapse (MVP) is a valvular heart disease characterized by the displacement of an abnormally thickened mitral valve leaflet into the left atrium during systole. [4] It is the primary form of myxomatous degeneration of the valve.