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  2. DNA synthesis - Wikipedia

    en.wikipedia.org/wiki/DNA_synthesis

    DNA replication also works by using a DNA template, the DNA double helix unwinds during replication, exposing unpaired bases for new nucleotides to hydrogen bond to. Gene synthesis, however, does not require a DNA template and genes are assembled de novo. DNA synthesis occurs in all eukaryotes and prokaryotes, as well as some viruses. The ...

  3. File:Steps in DNA synthesis.svg - Wikipedia

    en.wikipedia.org/.../File:Steps_in_DNA_synthesis.svg

    English: This diagram shows the synthesis of an Okazaki fragment on the lagging strand; synthesis on the leading strand is not shown but involves the same steps. (a) Helicase unwinds the DNA helix, and the resulting single-stranded DNA is coated with RPA proteins. (b) The polymerase alpha–primase synthesizes a short RNA–DNA primer in the 5 ...

  4. DNA replication - Wikipedia

    en.wikipedia.org/wiki/DNA_replication

    All known DNA replication systems require a free 3′ hydroxyl group before synthesis can be initiated (note: the DNA template is read in 3′ to 5′ direction whereas a new strand is synthesized in the 5′ to 3′ direction—this is often confused). Four distinct mechanisms for DNA synthesis are recognized: [citation needed]

  5. S phase - Wikipedia

    en.wikipedia.org/wiki/S_phase

    S phase (Synthesis phase) is the phase of the cell cycle in which DNA is replicated, occurring between G 1 phase and G 2 phase. [1] Since accurate duplication of the genome is critical to successful cell division, the processes that occur during S-phase are tightly regulated and widely conserved.

  6. Prokaryotic DNA replication - Wikipedia

    en.wikipedia.org/wiki/Prokaryotic_DNA_replication

    The rate of DNA replication in a living cell was first measured as the rate of phage T4 DNA elongation in phage-infected E. coli. [18] During the period of exponential DNA increase at 37 °C, the rate was 749 nucleotides per second. The mutation rate per base pair per replication during phage T4 DNA synthesis is 1.7 per 10 8. [19]

  7. Biosynthesis - Wikipedia

    en.wikipedia.org/wiki/Biosynthesis

    DNA synthesis, which takes place in the nucleus, is a semiconservative process, which means that the resulting DNA molecule contains an original strand from the parent structure and a new strand. [22] DNA synthesis is catalyzed by a family of DNA polymerases that require four deoxynucleoside triphosphates, a template strand, and a primer with a ...

  8. Eukaryotic DNA replication - Wikipedia

    en.wikipedia.org/wiki/Eukaryotic_DNA_replication

    Owing to the relatively short nature of the eukaryotic Okazaki fragment, DNA replication synthesis occurring discontinuously on the lagging strand is less efficient and more time-consuming than leading-strand synthesis. DNA synthesis is complete once all RNA primers are removed and nicks are repaired. Depiction of DNA replication at replication ...

  9. File:DNA replication en.svg - Wikipedia

    en.wikipedia.org/wiki/File:DNA_replication_en.svg

    The factual accuracy of this diagram or the file name is disputed. ... DNA replication or DNA synthesis is the process of copying a double-stranded DNA molecule.