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Silibinin (), also known as silybin (both from Silybum, the generic name of the plant from which it is extracted), is the major active constituent of silymarin, a standardized extract of the milk thistle, containing a mixture of flavonolignans consisting of silibinin, isosilibinin, silychristin, silidianin, and others.
Silybum marianum is a species of thistle.It has various common names including milk thistle, [1] blessed milkthistle, [2] Marian thistle, Mary thistle, Saint Mary's thistle, Mediterranean milk thistle, variegated thistle and Scotch thistle (not to be confused with Onopordum acanthium or Cirsium vulgare).
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Milk thistle is believed to give some remedy for liver diseases (e.g. viral hepatitis) and the extract, silymarin, is used in medicine. Mild gastrointestinal distress is the most common adverse event reported for milk thistle. The incidence is the same as for placebo. [10] A laxative effect for milk thistle has also been reported infrequently. [11]
It is also found in the silymarin extract from the milk thistle seeds. Taxifolin is present in vinegars aged in cherry wood. [7] Taxifolin, and flavonoids in general, can be found in many beverages and products. Specifically, taxifolin is found in plant-based foods like fruit, vegetables, wine, tea, and cocoa. [8]
Acetogenins are a class of polyketide natural products found in plants of the family Annonaceae. They are characterized by linear 32- or 34-carbon chains containing oxygenated functional groups including hydroxyls, ketones, epoxides, tetrahydrofurans and tetrahydropyrans. They are often terminated with a lactone or butenolide. [1]
Ketones are produced by the liver as part of fat metabolism and are normally not found in sufficient quantity to be measured in the urine or blood of non-diabetics or well-controlled diabetics. [74] The body normally uses glucose as its fuel and is able to do so with sufficient insulin levels.
Lactuca serriola, also called prickly lettuce, [2] milk thistle [2] (not to be confused with Silybum marianum, also called milk thistle), compass plant, [2] and scarole, [2] is an annual or biennial plant in the tribe Cichorieae within the family Asteraceae. It has a slightly fetid odor and is commonly considered a weed of orchards, roadsides ...