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  2. The Food and Drug Administration (FDA) has approved a new drug to treat amyotrophic lateral sclerosis (ALS)—and it’s controversial. The medication, called Relyvrio, was given the green light ...

  3. Maker of much-debated ALS drug says it may stop selling it ...

    www.aol.com/news/maker-much-debated-als-drug...

    The maker of a much-debated drug for Lou Gehrig’s disease said Friday its therapy failed to help patients in a large follow-up study, but stopped short of committing to follow through on a prior ...

  4. Amylyx's approved ALS drug flunks crucial test, shares dive - AOL

    www.aol.com/news/amylyxs-als-drug-fails-stage...

    The drug, branded as Relyvrio and the company's only product in market, was approved in September 2022 based on mid-stage trial data in 137 patients that showed the treatment slowed disease ...

  5. Sodium phenylbutyrate/ursodoxicoltaurine - Wikipedia

    en.wikipedia.org/wiki/Sodium_phenylbutyrate/urso...

    In March 2024, Amylyx Pharmaceuticals announced that its Phase III PHOENIX clinical trial of 664 American and European adults followed over 48 weeks showed no statistically significant difference in the functioning of ALS patients that were randomly assigned to treatment with Relyvrio, as compared to those receiving a placebo drug.

  6. ALS drug fails large clinical trial and may be withdrawn from ...

    www.aol.com/als-drug-fails-large-clinical...

    Amylyx Pharmaceuticals announced Friday that its drug for amyotrophic lateral sclerosis, or ALS, called Relyvrio, did not show significant benefit in a large clinical trial and may be withdrawn ...

  7. Riluzole - Wikipedia

    en.wikipedia.org/wiki/Riluzole

    Riluzole is a medication used to treat amyotrophic lateral sclerosis (ALS) and other motor neuron diseases. Riluzole delays the onset of ventilator-dependence or tracheostomy in some people and may increase survival by two to three months. [5] Riluzole is available in tablet and liquid form.

  8. Tofersen - Wikipedia

    en.wikipedia.org/wiki/Tofersen

    Tofersen, sold under the brand name Qalsody, is a medication used for the treatment of amyotrophic lateral sclerosis (ALS). [2] Tofersen is an antisense oligonucleotide that targets the production of superoxide dismutase 1 , an enzyme whose mutant form is commonly associated with amyotrophic lateral sclerosis.

  9. Amylyx (AMLX) Secures the FDA's Approval for ALS Drug - AOL

    www.aol.com/news/amylyx-amlx-secures-fdas...

    Amylyx (AMLX) obtains the FDA's approval for its oral, fixed-dose combination therapy for treating adults with amyotrophic lateral sclerosis (ALS) after a few roadblocks.