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Hepatitis B virus (HBV) is a partially double-stranded DNA virus, [1] a species of the genus Orthohepadnavirus and a member of the Hepadnaviridae family of viruses. [ 2 ] [ 3 ] This virus causes the disease hepatitis B .
The Hepatitis B virus (HBV) polymerase is a multifunctional enzyme, with both RNA-dependent and DNA-dependent polymerase functions, as well as an RNase H function. It acts on the HBV pre-genomic RNA (pgRNA) to reverse transcribe it to form a new rcDNA molecule within a new capsid. (The pgRNA has another function of being translated into the ...
820,000 resulting from hepatitis B (2019) [ 1 ] Hepatitis B is an infectious disease caused by the Hepatitis B virus (HBV) that affects the liver; [ 1 ][ 6 ] it is a type of viral hepatitis. [ 7 ] It can cause both acute and chronic infection. [ 1 ] Many people have no symptoms during an initial infection. For others, symptoms may appear 30 to ...
Hepatitis B vaccine is a vaccine that prevents hepatitis B. [ 13 ] The first dose is recommended within 24 hours of birth with either two or three more doses given after that. [ 13 ] This includes those with poor immune function such as from HIV/AIDS and those born premature. [ 13 ] It is also recommended that health-care workers be vaccinated ...
Hepadnaviridae[a] is a family of viruses. [2] Humans, apes, and birds serve as natural hosts. There are currently 18 species in this family, divided among 5 genera. [3] Its best-known member is hepatitis B virus. Diseases associated with this family include: liver infections, such as hepatitis, hepatocellular carcinomas (chronic infections ...
HBeAg is a hepatitis B viral protein, produced by the HBcAg reading frame. It is an indicator of active viral replication; this means the person infected with Hepatitis B can likely transmit the virus on to another person (i.e. the person is infectious). HBeAg is considered a marker for cccDNA replication. [1]