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Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine, with Crohn's disease and ulcerative colitis (UC) being the principal types. [3] Crohn's disease affects the small intestine and large intestine, as well as the mouth, esophagus, stomach and the anus, whereas UC primarily affects the colon ...
Hirschsprung's disease: enlargement of the colon due to lack of development of autonomic ganglia. Intestinal neuronal dysplasia: a disease of motor neurons leading to the bowels. Bowel obstruction: mechanical or functional obstruction of the bowel, most commonly due to adhesions, hernias or neoplasms.
Crohn's disease is a type of inflammatory bowel disease (IBD) that may affect any segment of the gastrointestinal tract. [3] Symptoms often include abdominal pain, diarrhea, fever, abdominal distension, and weight loss.
Ulcerative colitis (UC) is one of the two types of inflammatory bowel disease (IBD), with the other type being Crohn's disease. [1] It is a long-term condition that results in inflammation and ulcers of the colon and rectum. [1] [7] The primary symptoms of active disease are abdominal pain and diarrhea mixed with blood (hematochezia). [1]
Unlike the colon (or large bowel), which is rich with bacteria, the small bowel usually has fewer than 100,000 organisms per millilitre. [1] Patients with bacterial overgrowth typically develop symptoms which may include nausea, bloating, vomiting, diarrhea, malnutrition, weight loss, and malabsorption [2] by various mechanisms.
Worrisome or "alarm" features include onset at greater than 50 years of age, weight loss, blood in the stool, or a family history of inflammatory bowel disease. [7] Other conditions that may present similarly include celiac disease, microscopic colitis, inflammatory bowel disease, bile acid malabsorption, and colon cancer. [7]
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