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His trial on a few epilepsy patients in 1921 was the first use of the ketogenic diet as a treatment for epilepsy. [ 10 ] Wilder's colleague, paediatrician Mynie Gustav Peterman , later formulated the classic diet, with a ratio of one gram of protein per kilogram of body weight in children, 10–15 g of carbohydrate per day, and the remainder of ...
This discovery sparked the introduction of the MCT-ketogenic diet, a modification of the ketogenic diet. In the MCT-ketogenic diet, MCT oil is added to ketogenic meals, [35] which allows the carbohydrate content to be increased. The efficacy of the MCT ketogenic diet does not differ significantly from the classic ketogenic diet; however, not ...
Russell Morse Wilder Sr. (November 24, 1885 – December 16, 1959) [1] was an American physician, diabetologist, epileptologist, and medical researcher, known as one of the originators of the ketogenic ("classic keto") diet as a therapy for both epilepsy [2] [3] and diabetes. [4] [5] He coined the term "ketogenic diet."
This is an accepted version of this page This is the latest accepted revision, reviewed on 18 February 2025. Diets restricting carbohydrate consumption This article is about low-carbohydrate dieting as a lifestyle choice or for weight loss. For information on low-carbohydrate dieting as a therapy for epilepsy, see Ketogenic diet. An example of a low-carbohydrate dish, cooked kale and poached ...
A 2022 systematic review of the literature has found some evidence to support that a ketogenic diet or modified Atkins diet can be helpful in the treatment of epilepsy in some infants. [168] These types of diets may be beneficial for children with drug-resistant epilepsy; the use for adults remains uncertain. [6]
A diet high in fats and low in carbohydrates may also be beneficial, known as a ketogenic diet. Although diet adjustment can help, it does not eliminate the symptoms. Until a better form of treatment or cure is discovered, those with this disease will have myoclonic epilepsy for the rest of their lives. [6]
The effects of sustaining ketosis for up to two years are known from studies of people following a strict ketogenic diet for epilepsy or type 2 diabetes; these include short-term adverse effects leading to potential long-term ones. [20] However, literature on longer term effects of intermittent ketosis is lacking. [20]
It has been suggested that a low-carb, high fat ketogenic diet can be used to help treat epilepsy in children. [6] Additionally, ketone bodies can be anti-inflammatory. [ 19 ] Some kinds of cancer cells are unable to use ketone bodies, as they do not have the necessary enzymes to engage in ketolysis.