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Protein phosphatase 2 (PP2), also known as PP2A, is an enzyme that in humans is encoded by the PPP2CA gene. [ 2 ] [ 3 ] The PP2A heterotrimeric protein phosphatase is ubiquitously expressed, accounting for a large fraction of phosphatase activity in eukaryotic cells. [ 4 ]
Windows 10, version 22H2 is the only Windows 10 update to be eligible for the paid Extended Security Updates (ESU) program, which offers continued security updates until October 13, 2026 for consumers, or at most October 10, 2028 for businesses and schools.
APK is analogous to other software packages such as APPX in Microsoft Windows, APP for HarmonyOS or a Debian package in Debian-based operating systems.To make an APK file, a program for Android is first compiled using a tool such as Android Studio [3] or Visual Studio and then all of its parts are packaged into one container file.
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PP2 is a substance that has frequently been used in cancer research as a "selective" inhibitor for Src-family kinases. It strongly inhibits the kinases Lck ( IC 50 =4 nM ), Fyn (5 nM) and Hck (5 nM), shows weaker inhibition of EGFR (480 nM) and practically no inhibition of ZAP-70 (100 μM) and JAK2 (50 μM).