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Chemokines (from Ancient Greek χῠμείᾱ (khumeíā) 'alchemy' and κῑ́νησῐς (kī́nēsis) 'movement'), or chemotactic cytokines, are a family of small cytokines or signaling proteins secreted by cells that induce directional movement of leukocytes, as well as other cell types, including endothelial and epithelial cells.
More recently, enzyme molecules have also shown positive chemotactic behavior in the gradient of their substrates. [78] The thermodynamically favorable binding of enzymes to their specific substrates is recognized as the origin of enzymatic chemotaxis. [79] Additionally, enzymes in cascades have also shown substrate-driven chemotactic ...
Within this medical field is a special reversal form of drug delivery called chemotactic drug targeting. [ 1 ] [ 2 ] By using chemical agents to help guide a drug carrier to a specific location within the body, this innovative approach seeks to improve precision and control during the drug delivery process, decrease the risk of toxicity, and ...
In general, the most important requisite is to calibrate the incubation time of the assay both to the model cell and the ligand to be evaluated. Too short incubation time results in no cells in the sample, while too long time perturbs the concentration gradients and measures more chemokinetic than chemotactic responses.
By chemotactic selection we can determine whether a still not characterized molecule acts via the long- or the short-term receptor pathway. Recent results proved that chemokines (e.g. IL-8 , RANTES ) are working on long-term chemotaxis receptors, while vasoactive peptides (e.g. endothelin ) act more on the short-term ones.
Google Dictionary is an online dictionary service of Google that can be accessed with the "define" operator and other similar phrases [note 1] in Google Search. [2] It is also available in Google Translate and as a Google Chrome extension .
Pamela Anderson has recalled how she was allegedly once paid to attend Donald Trump’s birthday party as a Playmate. Anderson, who is Canadian and lives in British Columbia, appeared unimpressed ...
Google Translate is a multilingual neural machine translation service developed by Google to translate text, documents and websites from one language into another. It offers a website interface, a mobile app for Android and iOS, as well as an API that helps developers build browser extensions and software applications. [3]