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Starvation is a severe deficiency in caloric energy intake, below the level needed to maintain an organism's life. It is the most extreme form of malnutrition. In humans, prolonged starvation can cause permanent organ damage [1] and eventually, death. The term inanition [2] refers to the symptoms and effects of starvation.
Starvation response in animals (including humans) is a set of adaptive biochemical and physiological changes, triggered by lack of food or extreme weight loss, in which the body seeks to conserve energy by reducing metabolic rate and/or non-resting energy expenditure to prolong survival and preserve body fat and lean mass.
The syndrome can occur at the beginning of treatment for eating disorders when patients have an increase in calorie intake and can be fatal. It can also occur when someone does not eat for several days at a time usually beginning after 4–5 days with no food. [5] It can also occur after the onset of a severe illness or major surgery. The ...
Emaciation can be caused by undernutrition, malaria and cholera, tuberculosis and other infectious diseases with prolonged fever, parasitic infections, many forms of cancer and their treatments, lead poisoning, and eating disorders like anorexia nervosa.
The Mayo Clinic diet, a program that adheres to this notion, was developed by medical professionals based on scientific research, so you can trust that this program is based on science, and not ...
While catabolysis can be deadly over time, if the person is given medical treatment early enough, the effects of catabolysis can be reversed. However, the person may require intravenous nutrition, a blood transfusion, and/or oxygen replenishment. After that, it may be a few weeks to a few months before the person's muscle mass and fat deposits ...
Physiologist Ancel Keys was the lead investigator of the Minnesota Starvation Experiment. He was directly responsible for the X-ray analysis and administrative work and the general supervision of the activities in the Laboratory of Physiological Hygiene which he had founded at the University of Minnesota in 1940 after leaving positions at Harvard's Fatigue Laboratory and the Mayo Clinic.
Decreasing caloric intake by 20-30%, while fulfilling nutrient requirements, has been found to remedy diseases of aging, including cancer, cardiovascular disease, dementia, and diabetes in humans, and result in an average loss of 7.9 kilograms (17 lb) in body weight, but because of the long lifespan of humans, evidence that calorie restriction ...