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MGUS is a relatively stable condition afflicting 3% of people aged 50 and 5% of people aged 70; it progresses to multiple myeloma at a rate of 0.5–1% cases per year; smoldering multiple myeloma does so at a rate of 10% per year for the first 5 years, but then falls off sharply to 3% per year for the next 5 years and thereafter to 1% per year.
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Members of the IMWG conduct research to prevent onset of myeloma, improve treatment and find a cure. [8] The working group publishes statements and treatment guidelines in its own name [9] as well as sponsoring publications by its members. The IMF also has the Black Swan Research Initiative (BSRI) in order to work towards finding a cure for ...
Smouldering myeloma is a disease classified as intermediate in a spectrum of step-wise progressive diseases termed plasma cell dyscrasias.In this spectrum of diseases, a clone of plasma cells secreting monoclonal paraprotein (also termed myeloma protein or M protein) causes the relatively benign disease of monoclonal gammopathy of undetermined significance.
Serum protein electrophoresis showing a paraprotein (spike/peak in the gamma zone) in a patient with multiple myeloma.. A myeloma protein is an abnormal antibody (immunoglobulin) or (more often) a fragment thereof, such as an immunoglobulin light chain, that is produced in excess by an abnormal monoclonal proliferation of plasma cells, typically in multiple myeloma or Monoclonal gammopathy of ...
Myeloma Canada is the only national non-profit organization uniquely devoted to the Canadian myeloma community. The organization helps myeloma patients and raises awareness about this rare form of cancer. [1] Founded in 2005 by two myeloma patients, Myeloma Canada is a patient-driven, patient-focused, grassroots organization, whose goal is to:
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