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The pharmacological results from cerivastatin show that it is the most active HMG-CoA-reductase inhibitor among reported statins. Due to its high enzyme affinity, it would seem to offer ultra-low dose therapy in the microgram range. However, due to its relatively severe adverse effects in comparison to other statins, its market use was ...
Rosuvastatin, sold under the brand name Crestor among others, is a statin medication, used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. [6] It is recommended to be used together with dietary changes, exercise, and weight loss. [6] It is taken orally (by mouth). [6]
Some statins may also alter the concentrations of other medications, such as warfarin or digoxin, leading to alterations in effect or a requirement for clinical monitoring. [56] The increase in digoxin levels due to atorvastatin is a 1.2 fold elevation in the area under the curve (AUC), resulting in a minor
Statins are usually used to lower blood cholesterol levels and reduce risk for illnesses related to atherosclerosis, with a varying degree of effect depending on underlying risk factors and history of cardiovascular disease. [16]
The amygadala, prefrontal cortex and hypothalamus begin to change during pregnancy due to the high levels of stress experienced by the mother during this time. [ 35 ] In human mothers there was a correlation between increased gray matter volume in the substantia nigra and positive emotional feelings towards the infant.
Fertility is possible for both males and females with CAH but may be reduced due to multiple factors encompassing biology, psychology, social influences, and sexual aspects. [ 4 ] Management of CAH requires collaboration among different subspecialty professionals considering the complex nature of the disease's complications and long-term ...