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Degeneration theory achieved a detailed articulation in Bénédict Morel's Treatise on Degeneration of the Human Species (1857), a complicated work of clinical commentary from an asylum in Normandy (Saint Yon in Rouen) which, in the popular imagination at least, coalesced with de Gobineau's Essay on The Inequality of the Human Races (1855).
Wallerian degeneration occurs after axonal injury in both the peripheral nervous system (PNS) and central nervous system (CNS). It occurs in the section of the axon distal to the site of injury and usually begins within 24–36 hours of a lesion. Prior to degeneration, the distal section of the axon tends to remain electrically excitable.
Degeneration is deterioration in the medical sense. Generally, it is the change from a higher to a lower form. More specifically, it is the change of tissue to a lower or less functionally active form. True degeneration: when there is actual chemical change of the tissue itself.
Alzheimer's disease (AD) is a chronic neurodegenerative disease that results in the loss of neurons and synapses in the cerebral cortex and certain subcortical structures, resulting in gross atrophy of the temporal lobe, parietal lobe, and parts of the frontal cortex and cingulate gyrus. [14]
Examples of degeneracy are found in the genetic code, when many different nucleotide sequences encode the same polypeptide; in protein folding, when different polypeptides fold to be structurally and functionally equivalent; in protein functions, when overlapping binding functions and similar catalytic specificities are observed; in metabolism, when multiple, parallel biosynthetic and ...
Environmental degradation is the deterioration of the environment through depletion of resources such as quality of air, water and soil; the destruction of ecosystems; habitat destruction; the extinction of wildlife; and pollution. It is defined as any change or disturbance to the environment perceived to be deleterious or undesirable.
Degeneration (algebraic geometry), the act of taking a limit of a family of varieties; Degenerate bilinear form, a bilinear form on a vector space V whose induced map from V to the dual space of V is not an isomorphism; Degenerate distribution, the probability distribution of a random variable which only takes a single value
Muscle atrophy results from an imbalance between protein synthesis and protein degradation, although the mechanisms are incompletely understood and are variable depending on the cause. Muscle loss can be quantified with advanced imaging studies but this is not frequently pursued.