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The enzymes are from pigs. [5] Use is believed to be safe during pregnancy. [5] The components are digestive enzymes similar to those normally produced by the human pancreas. [6] They help the person digest fats, starches, and proteins. [5] Pancreatic enzymes have been used as medications since at least the 1800s. [7]
Treatment of CP consists of the administration of a solution of pancreatic enzymes with meals. Some patients do have pain reduction with enzyme replacement, and since they are relatively safe, giving enzyme replacement to a chronic pancreatitis patient is an acceptable step in treatment for most patients.
An exocrine pancreas cell is a pancreatic cell that produces enzymes that are secreted into the small intestine. These enzymes help digest food by releasing enzymes as it passes through the gastrointestinal tract. These include acinar cells, which secrete bicarbonate solution and mucin
The Pancreatic Cancer Action Network (PanCAN) is a United States–based 501(c)(3) charity that funds research, provides patient/caregiver support, conducts community outreach and advocates for increased federal research funding for those affected by pancreatic cancer. [4] [5]
In chronic pancreatitis, the fecal pancreatic elastase-1 (FPE-1) test is a marker of exocrine pancreatic function. Additional tests that may be useful in evaluating chronic pancreatitis include hemoglobin A1C , immunoglobulin G4 , rheumatoid factor , and anti-nuclear antibody .
Lifetime risk of cancer has been variously calculated as 35–54% [4] [5] [6] to the age of 75 years and screening for early pancreatic cancer is being offered to HP sufferers on a scientific basis. [7] Some patients may choose to have their pancreas surgically removed to prevent pancreatic cancer from developing in the future. [8]