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Progestogens, also sometimes written progestins, progestagens or gestagens, [1] are a class of natural or synthetic steroid hormones that bind to and activate the progesterone receptors (PR). [ 2 ] [ 3 ] Progesterone is the major and most important progestogen in the body.
Progesterone (/ p r oʊ ˈ dʒ ɛ s t ər oʊ n / ⓘ; P4) is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species.
Other contexts will include progestogens as a third class of sex steroids, distinct from androgens and estrogens. [5] Progesterone is the most important and only naturally occurring human progestogen. In general, androgens are considered "male sex hormones", since they have masculinizing effects, while estrogens and progestogens are considered ...
Hormones during pregnancy are the result of an intricate interaction between hormones generated by different glands and organs.The primary hormones involved comprise human chorionic gonadotropin (hCG), progesterone, estrogen, human placental lactogen (hPL), and oxytocin.
Progestogens are used most commonly in hormonal birth control and menopausal hormone therapy. [1] They can also be used in the treatment of gynecological conditions, to support fertility and pregnancy, to lower sex hormone levels for various purposes, and for other indications. [1] Progestogens are used alone or in combination with estrogens. [1]
5241 18667 Ensembl ENSG00000082175 ENSMUSG00000031870 UniProt P06401 Q00175 RefSeq (mRNA) NM_000926 NM_001202474 NM_001271161 NM_001271162 NM_008829 RefSeq (protein) NP_000917 NP_001189403 NP_001258090 NP_001258091 NP_032855 Location (UCSC) Chr 11: 101.03 – 101.13 Mb Chr 9: 8.9 – 8.97 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse The progesterone receptor (PR), also known as ...
Progesterone is a progestogen, or an agonist of the nuclear progesterone receptors (PRs), the PR-A, PR-B, and PR-C. [1] In one study, progesterone showed EC 50 Tooltip half-maximal effective concentration values of 7.7 nM for the human PR-A and 8.0 nM for the human PR-B. [5] In addition to the PRs, progesterone is an agonist of the membrane progesterone receptors (mPRs), including the mPRα ...
This is a list of progestogens that are or that have been used in clinical or veterinary medicine.