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Gastroesophageal reflux disease (GERD) or gastro-oesophageal reflux disease (GORD) is a chronic upper gastrointestinal disease in which stomach content persistently and regularly flows up into the esophagus, resulting in symptoms and/or complications.
In gastroenterology, esophageal pH monitoring is the current gold standard for diagnosis of gastroesophageal reflux disease (GERD). It provides direct physiologic measurement of acid in the esophagus and is the most objective method to document reflux disease, assess the severity of the disease and monitor the response of the disease to medical or surgical treatment.
Gastroesophageal reflux A condition that is a result of stomach contents consistently coming back up into the esophagus causing troublesome symptoms or complications. [ 19 ] Symptoms are considered troublesome based on how disruptive they are to a patient's daily life and well-being.
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It is the major symptom of gastroesophageal reflux disease (GERD). [6] Other common descriptors for heartburn (besides burning) are belching, nausea, squeezing, stabbing, or a sensation of pressure on the chest. The pain often rises in the chest (directly behind the breastbone) and may radiate to the neck, throat, or angle of the arm.
Gastroesophageal reflux disease is usually assumed to be caused by inflammation from gastric acid reflux which irritates the mucosa. One study suggests that the pathogenesis of may be cytokine-mediated. [6] Microscopic Slide of Infectious Esophagitis. Infectious esophagitis. Esophagitis happens due to a viral, fungal, parasitic or bacterial ...
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