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In each case, the patients found that the ketogenic diet was more effective for treating their disorder than medication and were able to discontinue the use of medication. The key to efficacy appears to be ketosis , which can be achieved either with a classic high-fat ketogenic diet, or with a low-carbohydrate diet similar to the induction ...
“The ketogenic diet is an evidence-based treatment for weight loss, Type 2 diabetes and epilepsy. ... Palmer said it’s “absolutely not” as simple as the keto diet fixes bipolar disorder or ...
Kynurenic acid is reduced in individuals with mood disorders, such as major depressive disorder [12] and bipolar disorder, [12] especially during depressive episodes. [ 13 ] High levels of kynurenic acid have been identified in human urine in certain metabolic disorders, such as marked pyridoxine deficiency and deficiency/absence of kynureninase .
By 2007, the ketogenic diet was available from around 75 centres in 45 countries, and less restrictive variants, such as the modified Atkins diet, were in use, particularly among older children and adults. The ketogenic diet was also under investigation for the treatment of a wide variety of disorders other than epilepsy. [1]
The ketogenic diet consists of a high-fat, low-carbohydrate diet, and has shown good results in patients whose epilepsy has not responded to medications and who cannot receive surgery. The vagus nerve stimulator is a device that can be implanted into patients with epilepsy, especially that which originates from a specific part of the brain .
Omega-3 fatty acids It is also conjectured that omega-3 fatty acids may have a mood stabilizing effect. [16] Compared with placebo, omega-3 fatty acids appear better able to augment known mood stabilizers in reducing depressive (but perhaps not manic) symptoms of bipolar disorder; additional trials would be needed to establish the effects of omega-3 fatty acids alone.