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  2. Your Gout Guide: From Symptoms to Treatment - AOL

    www.aol.com/lifestyle/gout-guide-symptoms...

    Gout in hands is less common but can happen. In this situation, it usually affects small joints in the fingers. ... Having high levels of uric acid in the body can cause gout in the feet or other ...

  3. Valsartan - Wikipedia

    en.wikipedia.org/wiki/Valsartan

    Valsartan, sold under the brand name Diovan among others, is a medication used to treat high blood pressure, heart failure, and diabetic kidney disease. [8] It belongs to a class of medications referred to as angiotensin II receptor blockers (ARBs).

  4. Monoarthritis - Wikipedia

    en.wikipedia.org/wiki/Monoarthritis

    Gout is inflammation caused by the deposition of needle-shaped monosodium urate crystals in the joints. It is the most common type of inflammatory arthritis in the United States. The disease typically affects a single joint in earlier stages but can progress into polyarthritis over time.

  5. Gout - Wikipedia

    en.wikipedia.org/wiki/Gout

    Arms and hands of a 50-year-old man, showing large tophi of sodium urate affecting the elbow, knuckles, and finger joints. The crystallization of uric acid, often related to relatively high levels in the blood, is the underlying cause of gout. This can occur because of diet, genetic predisposition, or underexcretion of urate, the salts of uric ...

  6. Managing Out-of-Control Chronic Gout: Going Beyond Oral ...

    www.aol.com/lifestyle/managing-control-chronic...

    The post Managing Out-of-Control Chronic Gout: Going Beyond Oral Treatments appeared first on Reader's Digest. Do you sometimes have severe, unexplained pain in your joints, particularly in your ...

  7. Tophus - Wikipedia

    en.wikipedia.org/wiki/Tophus

    Without treatment, tophi may develop on average about ten years after the onset of gout, although their first appearance can range from three to forty-two years. The development of gouty tophi can also limit joint function and cause bone destruction, leading to noticeable disabilities, especially when gout cannot successfully be treated. [ 2 ]

  8. Uricosuric - Wikipedia

    en.wikipedia.org/wiki/Uricosuric

    Uricosurics are often used in the treatment of gout, a disease in which uric acid crystals form deposits in the joints. By decreasing plasma uric acid levels, help dissolve these crystals, while limiting the formation of new ones. However, the increased uric acid levels in urine can contribute to kidney stones.

  9. Sacubitril/valsartan - Wikipedia

    en.wikipedia.org/wiki/Sacubitril/valsartan

    Sacubitril/valsartan is co-crystallized sacubitril and valsartan, in a one-to-one molar ratio. One sacubitril/valsartan complex consists of six sacubitril anions, six valsartan dianions, 18 sodium cations, and 15 molecules of water, resulting in the molecular formula C 288 H 330 N 36 Na 18 O 48 ·15H 2 O and a molecular mass of 5748.03 g/mol ...