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In biology, a marker gene may have several meanings. In nuclear biology and molecular biology, a marker gene is a gene used to determine if a nucleic acid sequence has been successfully inserted into an organism's DNA. In particular, there are two sub-types of these marker genes: a selectable marker and a marker for screening.
AQA Education, [1] trading as AQA (formerly the Assessment and Qualifications Alliance), is an awarding body in England, Wales and Northern Ireland. It compiles specifications and holds examinations in various subjects at GCSE, AS and A Level and offers vocational qualifications. AQA is a registered charity and independent of the government.
For example, DNA is a molecular marker that gives information about the organism from which it was taken. For another example, some proteins can be molecular markers of Alzheimer's disease in a person from which they are taken. [1] Molecular markers may be non-biological. Non-biological markers are often used in environmental studies. [2]
However, in the Physics paper 1 exam, a topic that was stated as "Not Assessed" came up; AQA accepted the mistake and awarded all students the full 9 marks to the question. [70] Also, in 2022, a question on one of the higher Maths papers was leaked hours before students sat them.
Cap analysis of gene expression (CAGE) is a gene expression technique used in molecular biology to produce a snapshot of the 5′ end of the messenger RNA population in a biological sample (the transcriptome).
[5] [6] Other variations tend to start with the mythical king, with one author noting "The nonsense about King Philip, or some ribald version of it, has been memorized by generations of biology students". [7] Dear King Philip Claps Often For Good Science; Dark King Prawns Curl Over Fresh Green Salad; Do Kings Play Chess On Fine Green Silk? [8]: 69
In quantitative ELISA, the optical density (OD) of the sample is compared to a standard curve, which is typically a serial dilution of a known-concentration solution of the target molecule. For example, if a test sample returns an OD of 1.0, the point on the standard curve that gave OD = 1.0 must be of the same analyte concentration as the sample.
Balancer chromosomes were first used in the fruit fly by Hermann Muller, who pioneered the use of radiation for organismal mutagenesis. [2]In the modern usage of balancer chromosomes, random mutations are first induced by exposing living organisms with otherwise normal chromosomes to substances which cause DNA damage; in flies and nematodes, this usually occurs by feeding larvae ethyl ...