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  2. Autoimmunity - Wikipedia

    en.wikipedia.org/wiki/Autoimmunity

    The decreased ability of the immune system to clear infections in these patients may be responsible for causing autoimmunity through perpetual immune system activation. [ 14 ] One example is common variable immunodeficiency , in which multiple autoimmune diseases are seen, e.g., inflammatory bowel disease, autoimmune thrombocytopenia and ...

  3. Autoimmune disease - Wikipedia

    en.wikipedia.org/wiki/Autoimmune_disease

    A key difference is a malfunction of the innate immune system in autoinflammatory diseases, whereas in autoimmune diseases there is a malfunction of the adaptive immune system. [8] Symptoms of autoimmune diseases can significantly vary, primarily based on the specific type of the disease and the body part that it affects.

  4. Immune disorder - Wikipedia

    en.wikipedia.org/wiki/Immune_disorder

    An immune disorder is a dysfunction of the immune system. [1] These disorders can be characterized in several different ways: By the component(s) of the immune system affected; By whether the immune system is overactive or underactive; By whether the condition is congenital or acquired

  5. Relapsing polychondritis - Wikipedia

    en.wikipedia.org/wiki/Relapsing_polychondritis

    Relapsing polychondritis is an autoimmune disease [11] in which the body's immune system begins to attack and destroy the cartilage tissues in the body. It has been postulated that both cell-mediated immunity and humoral immunity are responsible. [7] Reasons for disease onset are not known.

  6. Type 1 diabetes - Wikipedia

    en.wikipedia.org/wiki/Type_1_diabetes

    Type 1 diabetes (T1D), formerly known as juvenile diabetes, is an autoimmune disease that occurs when pancreatic cells (beta cells) are destroyed by the body's immune system. [5] In healthy persons, beta cells produce insulin .

  7. Immunopathology - Wikipedia

    en.wikipedia.org/wiki/Immunopathology

    A few examples of autoimmune diseases are Type 1 diabetes, Addison's disease and Celiac disease. The third and final type of complication with the immune system is Immunodeficiency, where the immune system lacks the ability to fight off a certain disease. The immune system's ability to combat it is either hindered or completely absent.

  8. Lupus - Wikipedia

    en.wikipedia.org/wiki/Lupus

    Lupus, formally called systemic lupus erythematosus (SLE), is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body. [1] Symptoms vary among people and may be mild to severe. [1]

  9. Immune dysregulation - Wikipedia

    en.wikipedia.org/wiki/Immune_dysregulation

    The lack of naïve T lymphocytes is the cause of low plasticity of the immune system in the elderly. [11] In aging of the immune system is also a decrease in central tolerance and an increase in the number of autoreactive T cells. [12] B cells also have a decreased repertoire of naïve cells and an increase in memory B cells. [13]