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The previous treatment options had many shortcomings, and the introduction of biological therapy changed the way physicians treat Crohn's disease and ulcerative colitis. [ 5 ] [ 6 ] Even so, biologic therapy still has its faults such as high cost and risk of side effects.
Participants in the trial were ages 18 or older and either had a dependence on glucocorticoids for treatment or had not had success with certain medications for ulcerative colitis treatment.
Standard treatment for ulcerative colitis depends on the extent of involvement and disease severity. The goal is to induce remission initially with medications, followed by the administration of maintenance medications to prevent a relapse. The concept of induction of remission and maintenance of remission is very important.
Management of ulcerative colitis involves first treating the acute symptoms of the disease, then maintaining remission. Ulcerative colitis is a form of colitis , a disease of the intestine , specifically the large intestine or colon , that includes characteristic ulcers , or open sores, in the colon.
Mirikizumab, a drug currently approved by the Food and Drug Administration (FDA) for the treatment of ulcerative colitis, also sends Crohn's disease into clinical remission, new findings suggest.
Ulcerative colitis is a condition that leads to ulcers and causes abdominal pain, bloody stools and incontinence. It affects around 1.25 million people in the United States, according to Pfizer.
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