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U.S. Route 72 (US 72) is an east–west United States highway that travels for 317.811 miles (511.467 km) from southwestern Tennessee, throughout North Mississippi, North Alabama, and southeastern Tennessee. The highway's western terminus is in Memphis, Tennessee and its eastern terminus is in Chattanooga. It is the only U.S. Highway to begin ...
Corridor W is a highway in the U.S. states of South Carolina and North Carolina. It is routed entirely along U.S. Route 25 (US 25); from Interstate 85 (I-85), in Greenville, South Carolina, to I-26, near East Flat Rock, North Carolina. The entire corridor is four-lane, that is expressway grade in South Carolina and freeway grade in North ...
U.S. Route 321 (US 321) is a spur of U.S. Route 21.It runs for 516.9 miles (831.9 km) from Hardeeville, South Carolina to Lenoir City, Tennessee; with both serving as southern termini.
As road closures are expected to last for months, the Tennessee Department of Transportation is warning people to avoid roads between East Tennessee and Western North Carolina.
Interstate 81 offers a bypass to I-40. From Knoxville, travelers can head north on I-81, which connects with Interstate 26, providing an alternate route to Asheville and other areas in North Carolina.
U.S. Route 411 (US 411) is an alternate parallel-highway associated with US 11.It extends for about 309.7 miles (498.4 km) from US 78 in Leeds, Alabama, to US 25W/US 70 in Newport, Tennessee.