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3578 16198 Ensembl ENSG00000145839 ENSMUSG00000021538 UniProt P15248 P15247 RefSeq (mRNA) NM_000590 NM_008373 RefSeq (protein) NP_000581 NP_032399 Location (UCSC) Chr 5: 135.89 – 135.9 Mb Chr 13: 56.63 – 56.63 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Interleukin 9, also known as IL-9, is a pleiotropic cytokine (cell signalling molecule) belonging to the group of ...
asthma Apolizumab [21] mab: humanized: HLA-DR: hematological cancers: Aprutumab ixadotin [22] mab: human: FGFR2: Arcitumomab [23] CEA-Scan: Fab' mouse: Carcinoembryonic antigen (CEA) gastrointestinal cancers (diagnosis) Ascrinvacumab [12] mab: human: activin receptor-like kinase 1: cancer Aselizumab [24] mab: humanized: L-selectin (CD62L ...
For example, the clinical trial results of omalizumab on asthma have unambiguously settled the long debate on whether IgE plays a central role in the pathogenesis of asthma. [29] Numerous investigator-initiated case studies or small-scale pilot studies of omalizumab have been performed on various allergic diseases and several non-allergic ...
Interleukin 9 (IL-9) [30] is a cytokine that supports IL-2 independent and IL-4 independent growth of helper T cells. Early studies had indicated that Interleukin 9 and 7 seem to be evolutionary related [ 31 ] and Pfam, InterPro and PROSITE entries exist for interleukin 7/interleukin 9 family.
An anti-asthmatic agent, also known as an anti-asthma drug, refers to a drug that can aid in airway smooth muscle dilation to allow normal breathing during an asthma attack or reduce inflammation on the airway to decrease airway resistance for asthmatic patients, or both. The goal of asthmatic agents is to reduce asthma exacerbation frequencies ...
More than ten percent of people taking Anakinra have injection site reactions, headaches, and have increased cholesterol levels. [1] Recipients have eight percent more patients decrease white blood cells counts, two percent more patients decrease platelets counts, one percent more patients get severe infections (4.5% for patients with asthma compared to 0% placebo patients with asthma). [1]
Interleukin 9 receptor (IL9R) also known as CD129 (Cluster of Differentiation 129) is a type I cytokine receptor. IL9R also denotes its human gene. [5] The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as ...
Pitrakinra (trade name Aerovant) is a 15-kDa human recombinant protein of wild-type human interleukin-4 (IL-4). It is an IL-4 and IL-13 antagonist that has been studied in a phase IIb clinical trial for the treatment of asthma. Two point mutations on pitrakinra (position 121 mutated from arginine to aspartic acid and position 124 mutated from ...