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  2. PTPRC - Wikipedia

    en.wikipedia.org/wiki/PTPRC

    The CD45 protein family consists of multiple members that are all products of a single complex gene. This gene contains 34 exons, producing a massive protein with extracellular and cytoplasmic domains that are both unusually large. Exons 4, 5, and 6 (corresponding to protein regions A, B, and C) are alternatively spliced to generate up to eight ...

  3. Cluster of differentiation - Wikipedia

    en.wikipedia.org/wiki/Cluster_of_differentiation

    The CD nomenclature was proposed and established in the 1st International Workshop and Conference on Human Leukocyte Differentiation Antigens (HLDA), held in Paris in 1982. [4] [5] This system was intended for the classification of the many monoclonal antibodies (mAbs) generated by different laboratories around the world against epitopes on the surface molecules of leukocytes (white blood cells).

  4. List of human blood components - Wikipedia

    en.wikipedia.org/wiki/List_of_human_blood_components

    Blood plasma protein 3.5-5.0 ... social high 0.5 × 10 −3: reduced coordination ... Reference ranges for common blood tests; References

  5. Serum protein electrophoresis - Wikipedia

    en.wikipedia.org/wiki/Serum_protein_electrophoresis

    Serum protein electrophoresis (SPEP or SPE) is a laboratory test that examines specific proteins in the blood called globulins. [1] The most common indications for a serum protein electrophoresis test are to diagnose or monitor multiple myeloma , a monoclonal gammopathy of uncertain significance (MGUS), or further investigate a discrepancy ...

  6. Reference ranges for blood tests - Wikipedia

    en.wikipedia.org/wiki/Reference_ranges_for_blood...

    Reference ranges (reference intervals) for blood tests are sets of values used by a health professional to interpret a set of medical test results from blood samples. Reference ranges for blood tests are studied within the field of clinical chemistry (also known as "clinical biochemistry", "chemical pathology" or "pure blood chemistry"), the ...

  7. PTPRCAP - Wikipedia

    en.wikipedia.org/wiki/PTPRCAP

    Protein tyrosine phosphatase receptor type C-associated protein is an enzyme that in humans is encoded by the PTPRCAP gene. [5] The protein encoded by this gene was identified as a transmembrane phosphoprotein specifically associated with tyrosine phosphatase PTPRC/CD45, a key regulator of T- and B-lymphocyte activation. The interaction with ...

  8. List of human clusters of differentiation - Wikipedia

    en.wikipedia.org/wiki/List_of_human_clusters_of...

    The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Used in histopathology, where it is known as EMA (epithelial membrane antigen), to identify various tumours etc. CD228: Melanotransferrin (MFI2). This protein is a cell-surface glycoprotein found on melanoma cells CD229

  9. Monoclonal B-cell lymphocytosis - Wikipedia

    en.wikipedia.org/wiki/Monoclonal_B-cell_lymphocy...

    Patients with this lymphoma commonly have an IgM gammaopathy, i.e. high blood levels of an IgM monoclonal protein. [6] Hairy cell leukemia: The monoclonal B-cells in this usually indolent CLL/SLL-like leukemia have a distinctive morphology and are CD5−, CD10−, CD19+, CD20+ (bright), CD23−, CD103+, CD200+, and complete Ig+. [9]