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Urinary tract infection in pediatric patients is a significant clinical issue, affecting approximately 7% of fevered infants and children. [43] If left untreated, the infection can ascend from the bladder to the kidneys, resulting in acute pyelonephritis, which leads to hypertension , kidney scarring , and end-stage kidney disease .
For instance, in ciprofloxacin, above, the R substituent attached to the N-1 atom is a cyclopropyl group, the R substituent in blue is a piperazine moiety, and the remaining substitution sites (R groups) are hydrogen atoms. Quinolones can be classified into generations based on their antibacterial spectrums.
It is particularly used for infections of the skin, respiratory system and mammary glands in dogs and cats, as well as with urinary tract infections. For dogs, a dose ranges from 2.75 - 5.5 mg/kg once a day. The duration of treatment is usually at least five days, longer if there is a concurrent fungal or yeast infection. [4]
Ciprofloxacin is a fluoroquinolone antibiotic used to treat a number of bacterial infections. [5] This includes bone and joint infections, intra-abdominal infections, certain types of infectious diarrhea, respiratory tract infections, skin infections, typhoid fever, and urinary tract infections, among others. [5]
Dorsch R, Teichmann-Knorrn S, Sjetne Lund H. Urinary tract infection and subclinical bacteriuria in cats: A clinical update. J Feline Med Surg. 2019 Nov;21(11):1023-1038. doi: 10.1177 ...
Penicillin for cats is an antibiotic medication derived from the Penicillium fungi. It falls under the beta-lactam class of antibiotics and is primarily used to treat bacterial infections. The ...