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  2. Ringer's lactate solution - Wikipedia

    en.wikipedia.org/wiki/Ringer's_lactate_solution

    Ringer's lactate solution is in the crystalloid family of medications. [5] It is isotonic, i.e. it has the same tonicity as blood. [2] Ringer's solution was invented in the 1880s; lactate was added in the 1930s. [4] It is on the World Health Organization's List of Essential Medicines. [6] Lactated Ringer's is available as a generic medication. [1]

  3. Ringer's solution - Wikipedia

    en.wikipedia.org/wiki/Ringer's_solution

    Ringer's solution is a solution of several salts dissolved in water for the purpose of creating an isotonic solution relative to the body fluids of an animal. Ringer's solution typically contains sodium chloride , potassium chloride , calcium chloride and sodium bicarbonate , with the last used to buffer the pH .

  4. Volume expander - Wikipedia

    en.wikipedia.org/wiki/Volume_expander

    Lactated Ringer's solution contains 28 mmol/L lactate, 4 mmol/L K + and 1.5 mmol/L Ca 2+. It is very similar – though not identical – to Hartmann's solution, the ionic concentrations of which differ slightly.

  5. FDA declares IV fluid shortage in the wake of Helene - AOL

    www.aol.com/news/fda-declares-iv-fluid-shortage...

    Confirming concerns that sprang up after the storm, the FDA declared shortages of Dextrose 70% IV Solution, Lactated Ringers IV Solution and… FDA declares IV fluid shortage in the wake of Helene ...

  6. Sodium lactate - Wikipedia

    en.wikipedia.org/wiki/Sodium_lactate

    Sodium lactate is used to treat arrhythmias caused by overdosing of class I antiarrythmics, as well as pressor sympathomimetics which can cause hypertension. [10]It can be given intravenously as a source of bicarbonate for preventing or controlling mild to moderate metabolic acidosis in patients with restricted oral intake (for sodium bicarbonate) whose oxidative processes are not seriously ...

  7. Parkland formula - Wikipedia

    en.wikipedia.org/wiki/Parkland_formula

    [1] [2] [3] The milliliter amount of fluid required for the first 24 hours – usually Lactated Ringer's – is four times the product of the body weight and the burn percentage (i.e. body surface area affected by burns). [4] The first half of the fluid is given within eight hours from the burn incident, and the remaining over the next 16 hours.

  8. Loading dose - Wikipedia

    en.wikipedia.org/wiki/Loading_dose

    In pharmacokinetics, a loading dose is an initial higher dose of a drug that may be given at the beginning of a course of treatment before dropping down to a lower maintenance dose. [1] A loading dose is most useful for drugs that are eliminated from the body relatively slowly, i.e. have a long systemic half-life.

  9. Physiologically based pharmacokinetic modelling - Wikipedia

    en.wikipedia.org/wiki/Physiologically_based...

    The model equations follow the principles of mass transport, fluid dynamics, and biochemistry in order to simulate the fate of a substance in the body. [9] Compartments are usually defined by grouping organs or tissues with similar blood perfusion rate and lipid content (i.e. organs for which chemicals' concentration vs. time profiles will be similar).