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High-grade prostatic intraepithelial neoplasia (HGPIN) is an abnormality of prostatic glands and believed to precede the development of prostate adenocarcinoma (the most common form of prostate cancer). [1] [2] It may be referred to simply as prostatic intraepithelial neoplasia (PIN).
Body roundness index (BRI) is a calculated geometric index used to quantify an aspect of a person's individual body shape.Based on the principle of body eccentricity, it provides a rapid visual and anthropometric tool for health evaluation.
Due to the rising prevalence of obesity in children and its many adverse health effects it is being recognized as a serious public health concern. [1] The term overweight rather than obese is often used when discussing childhood obesity, as it is less stigmatizing, although the term overweight can also refer to a different BMI category. [2]
Some health risks associated with childhood obesity include high blood pressure, high cholesterol levels, insulin resistance and type 2 diabetes. These factors may eventually lead to further complications such as heart attack, stroke, a variety of cardiovascular conditions and if not treated properly and in a timely manner may ultimately result ...
The Gleason grading system is used to help evaluate the prognosis of men with prostate cancer using samples from a prostate biopsy. Together with other parameters, it is incorporated into a strategy of prostate cancer staging which predicts prognosis and helps guide therapy. A Gleason score is given to prostate cancer based upon its microscopic ...
The healthy BMI range varies with the age and sex of the child. Obesity in children and adolescents is defined as a BMI greater than the 95th percentile. [47] The reference data that these percentiles are based on is from 1963 to 1994 and thus has not been affected by the recent increases in rates of obesity. [48]
However, high magnification (right image) shows the key feature of prominent nucleoli (visible at 200x magnification to make the diagnosis of "high-grade"), as well as other typical features of HGPIN. Reference for features: - Margaret Sanders, M.B.B.Ch., Murali Varma, M.B.B.S.. High grade prostatic intraepithelial neoplasia (HGPIN).
It plays a role in assessing whether the intrauterine growth restriction of a child is symmetrical or asymmetrical. [ 14 ] CI has been shown to have higher sensitivity, specificity, and positive and negative predictive values than body mass index for determining adiposity .