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The definition of prebiotics and the food ingredients that can fall under this classification, has evolved since its first definition in 1995. [3] In its earliest definition, the term prebiotics was used to refer to non-digestible food ingredients that were beneficial to the host through their selective stimulation of specific bacteria within the colon.
Most commonly, gummy supplements are made from gelatin, cornstarch, water and sugar, along with flavorings. [7]Although gummy vitamins are the most popular type of gummy supplements, they may also be derived from herbal supplements, containing extracts from plants like ashwagandha [8] and cannabis (e.g., CBD), [9] as well as the algae-derived astaxanthin.
A 2002 meta-analysis that included five double-blind trials examining the short-term (2–8 weeks) effects of a yogurt with probiotic strains on serum cholesterol levels found little effect of 8.5 mg/dL (0.22 mmol/L) (4% decrease) in total cholesterol concentration, and a decrease of 7.7 mg/dL (0.2 mmol/L) (5% decrease) in serum LDL concentration.
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