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  2. Melatonin as a medication and supplement - Wikipedia

    en.wikipedia.org/wiki/Melatonin_as_a_medication...

    Melatonin is thought to activate melatonin receptors in the suprachiasmatic nucleus of the hypothalamus to regulate the circadian clock and sleep–wake cycles. [21] When used several hours before sleep according to the phase response curve for melatonin in humans, small amounts (0.3 mg [ 56 ] ) of melatonin shift the circadian clock earlier ...

  3. Tetrahydrobiopterin - Wikipedia

    en.wikipedia.org/wiki/Tetrahydrobiopterin

    Tetrahydrobiopterin (BH 4, THB), also known as sapropterin (), [5] [6] is a cofactor of the three aromatic amino acid hydroxylase enzymes, [7] used in the degradation of amino acid phenylalanine and in the biosynthesis of the neurotransmitters serotonin (5-hydroxytryptamine, 5-HT), melatonin, dopamine, norepinephrine (noradrenaline), epinephrine (adrenaline), and is a cofactor for the ...

  4. Melatonin - Wikipedia

    en.wikipedia.org/wiki/Melatonin

    Melatonin, an indoleamine, is a natural compound produced by various organisms, including bacteria and eukaryotes. [1] Its discovery in 1958 by Aaron B. Lerner and colleagues stemmed from the isolation of a substance from the pineal gland of cows that could induce skin lightening in common frogs.

  5. Is melatonin or ashwagandha better for sleep? Experts weigh in

    www.aol.com/finance/melatonin-ashwagandha-better...

    For those who wake up in the middle of the night, he recommends a sustained release of a higher dose of melatonin. To reap the sleep benefits of ashwagandha, he says the supplement must be at ...

  6. Indolamines - Wikipedia

    en.wikipedia.org/wiki/Indolamines

    Tryptamine - otherwise known as indolamine. [citation needed]Indolamines are a family of neurotransmitters that share a common molecular structure.Indolamines are a classification of monoamine neurotransmitter, along with catecholamines and ethylamine derivatives.

  7. α-Methylmelatonin - Wikipedia

    en.wikipedia.org/wiki/Α-Methylmelatonin

    α-Methylmelatonin, also known as α-methyl-5-methoxy-N-acetyltryptamine, is a synthetic tryptamine derivative and analogue of the monoamine neurotransmitter melatonin. [1] It is a metabolite of α-methyltryptophan, α-methyl-5-hydroxytryptophan, and α-methylserotonin that can be formed in small amounts via aralkylamine N-acetyltransferase (AANAT).

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