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DMPA, under brand names such as Depo-Provera and Depo-SubQ Provera 104, is used in hormonal birth control as a long-lasting progestogen-only injectable contraceptive to prevent pregnancy in women. [ 38 ] [ 39 ] It is given by intramuscular or subcutaneous injection and forms a long-lasting depot , from which it is slowly released over a period ...
Medroxyprogesterone acetate (brand names Depo-Provera, Provera, Depo-subQ Provera 104) [4] – 150 mg (intramuscularly) or 104 mg (subcutaneously) every 3 months [3] Norethisterone enanthate (brand names NET EN, Noristerat, Norigest, Doryxas) [ 5 ] – 200 mg (intramuscularly) every 2 months [ 3 ]
Progestogen-only medications, including progestogen-only pills and a slow-release (depot) injectable medication, depot medroxyprogesterone acetate (DMPA; Depo-Provera) do not contain an estrogen. DMPA is given as an injection every 90 days, and is typically associated with amenorrhea in about 50 to 60% of users at the end of one year.
Contraceptive Technology reports a typical failure rate of 3% per year for the injection Depo-Provera, and 8% per year for most other user-dependent hormonal methods. [10] While no large studies have been done, it is hoped that newer methods which require less frequent action (such as the patch) will result in higher user compliance and ...
Amenorrhea or amenorrhoea is the absence of a menstrual period in a female who has reached reproductive age. [1] Physiological states of amenorrhoea are most commonly seen during pregnancy and lactation ( breastfeeding ).
Common side effects of EC/MPA include irregular menstrual periods which typically improves with time. [3] Other side effects include blood clots, headache, hair loss, depression, nausea, and breast pain. [3] [4] Use during pregnancy is not recommended. [2] Use during breastfeeding is likely safe. [5] It works mainly by preventing ovulation. [2]
[1] [2] Other side effects of progestogens may include an increased risk of breast cancer, cardiovascular disease, and blood clots. [2] At high doses, progestogens can cause low sex hormone levels and associated side effects like sexual dysfunction and an increased risk of bone fractures .
It found the effects of fish oil and vitamin B 12 to be unknown. [54] Reviews found tentative evidence that ginger powder may be effective for primary dysmenorrhea. [ 55 ] Reviews have found promising evidence for Chinese herbal medicine for primary dysmenorrhea, but that the evidence was limited by its poor methodological quality.
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