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Adipsia, also known as hypodipsia, is a symptom of inappropriately decreased or absent feelings of thirst. [ 1 ] [ 2 ] It involves an increased osmolality or concentration of solute in the urine, which stimulates secretion of antidiuretic hormone (ADH) from the hypothalamus to the kidneys.
Therefore, significant hypernatremia should be treated carefully by a physician or other medical professional with experience in treatment of electrolyte imbalance. Specific treatments such as thiazide diuretics (e.g., chlorthalidone) in congestive heart failure or corticosteroids in nephropathy also can be used. [19]
In adults over the age of 50 years, the body's thirst sensation reduces and continues diminishing with age, putting this population at increased risk of dehydration. [6] Several studies have demonstrated that elderly persons have lower total water intakes than younger adults, and that women are particularly at risk of too low an intake.
Most people can tolerate a 3-4% decrease in total body water without difficulty or adverse health effects. A 5-8% decrease can cause fatigue and dizziness. Loss of over 10% of total body water can cause physical and mental deterioration, accompanied by severe thirst. Death occurs with a 15 and 25% loss of body water. [4]
The first symptoms of kidney failure are silent. Failing kidneys can’t remove extra fluid from the body, nor can they filter molecules like urea, which can be toxic in high dosages, from the blood.
Signs and symptoms of psychogenic polydipsia include: [3] Excessive thirst and xerostomia, leading to overconsumption of water; Hyponatraemia, causing headache, muscular weakness, twitching, confusion, vomiting, irritability etc., although this is only seen in 20–30% of cases.