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Childhood-onset nephrotic syndrome is a kidney disorder characterized by severe proteinuria (excess proteins in the urine), hypoalbuminemia (low albumin levels in the blood), and edema (swelling) that affects approximately 2-7 per 100,000 children under 18 years of age annually.
Nephrotic syndrome is a collection of symptoms due to kidney damage. This includes protein in the urine , low blood albumin levels , high blood lipids , and significant swelling . Other symptoms may include weight gain, feeling tired, and foamy urine.
It is characterized by nephrotic syndrome and diffuse scarring of the glomeruli. It is particularly associated with poorly managed diabetes mellitus and is a primary reason for dialysis in many developed countries. It is classified as a small blood vessel complication of diabetes. [7]
Rapidly progressive glomerulonephritis (RPGN) is a syndrome of the kidney that is characterized by a rapid loss of kidney function, [4] [5] (usually a 50% decline in the glomerular filtration rate (GFR) within 3 months) [5] with glomerular crescent formation seen in at least 50% [5] or 75% [4] of glomeruli seen on kidney biopsies.
FSGS accounts for 35% of all cases of nephrotic syndrome, making it one of the most common causes of nephrotic syndrome in the United States. [8] FSGS accounts for 2% of all cases of kidney failure. [4] African American patients have four times the likelihood of developing FSGS. Men are about two times as likely to develop FSGS compared to ...
Minimal change disease (MCD), also known as lipoid nephrosis or nil disease, among others, is a disease affecting the kidneys which causes nephrotic syndrome. [1] Nephrotic syndrome leads to the loss of significant amounts of protein to the urine (proteinuria), which causes the widespread edema (soft tissue swelling) and impaired kidney function commonly experienced by those affected by the ...
Cardiorenal syndrome; CFHR5 nephropathy; Childhood-onset nephrotic syndrome; Chronic allograft nephropathy; Chronic kidney disease; Chronic kidney disease–mineral and bone disorder; CKDu in Sri Lanka; Congenital nephrotic syndrome; Conorenal syndrome; Contrast-induced nephropathy; Cystic kidney disease
In nephrotic syndrome, the glomerulus has been damaged so that a large amount of protein in the blood enters the urine. Other frequent features of the nephrotic syndrome include swelling, low serum albumin, and high cholesterol. Pyelonephritis is infection of the kidneys and is frequently caused by complication of a urinary tract infection.