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The Merkel cell's somewhat rigid structure, and the fact that they are not encapsulated, [clarification needed] causes them respond to a sustained adequate mechanical stimulus with sustained "firing" of action potentials (or spikes): they are slowly adapting (contrast with the rapidly adapting Pacinian and Meissner's corpuscles). [citation needed]
Merkel cell. Merkel cells are found in the skin and some parts of the mucosa of all vertebrates. In mammalian skin, they are clear cells found in the stratum basale [2] [3] (at the bottom of sweat duct ridges) of the epidermis approximately 10 μm in diameter. They are oval-shaped mechanoreceptors essential for light touch sensation and found ...
Merkel's Disks - Located on the upper part of the dermis. Slow adapting receptors. Found on the fingertips as well as the eyelids. Meissner's Corpuscles - Located also on the upper part of the dermis. Found on the hairless skin including the lips as well as the eyelids. These are rapid adapting receptors.
Tactile corpuscles or Meissner's corpuscles are a type of mechanoreceptor discovered by anatomist Georg Meissner (1829–1905) and Rudolf Wagner. [ 1 ] [ 2 ] This corpuscle is a type of nerve ending in the skin that is responsible for sensitivity to pressure .
The Slowly Adapting type 1 (SA1) mechanoreceptor, with the Merkel corpuscle end-organ (also known as Merkel discs) detect sustained pressure and underlies the perception of form and roughness on the skin. [1] They have small receptive fields and produce sustained responses to static stimulation. [citation needed]
Bulbous corpuscles react slowly and respond to sustained skin stretch. They are responsible for the feeling of object slippage and play a major role in the kinesthetic sense and control of finger position and movement. Merkel and bulbous cells - slow-response - are myelinated; the rest - fast-response - are not. All of these receptors are ...
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All cutaneous mechanoreceptors including pacinian corpuscles: III Aδ: 1–5 μm: Thin: 3–30 m/s: Free nerve endings of touch and pressure Nociceptors of neospinothalamic tract Cold thermoreceptors: IV C: 0.2–1.5 μm: No: 0.5–2.0 m/s: Nociceptors of paleospinothalamic tract Warmth receptors