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Franciscus Sylvius began differentiating between the various forms of tuberculosis (pulmonary, ganglion). He was the first person to recognize that the skin ulcers caused by scrofula resembled tubercles seen in phthisis, [ 48 ] noting that "phthisis is the scrofula of the lung" in his book Opera Medica , published posthumously in 1679.
Tuberculosis (TB), also known colloquially as the "white death", or historically as consumption, [7] is a contagious disease usually caused by Mycobacterium tuberculosis (MTB) bacteria. [1] Tuberculosis generally affects the lungs , but it can also affect other parts of the body. [ 1 ]
Mycobacterium tuberculosis (M. tb), also known as Koch's bacillus, is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis. [ 1 ] [ 2 ] First discovered in 1882 by Robert Koch , M. tuberculosis has an unusual, waxy coating on its cell surface primarily due to the presence of mycolic acid .
MTBVAC, [12] an attenuated form of Myobacterium tuberculosis. Phase II trials were completed in 2021 and 2022; phase III trials began in 2022 and will run until 2029. [13] [14] M72/AS01E, consisting of two fused tuberculosis bacillus protein antigens together with the adjuvant AS01. It is intended to prevent tuberculosis in people with a latent ...
The Tuberculosis Movement : A Public Health Campaign in the Progressive Era (1988) Tomes, Nancy. "The private side of public health: sanitary science, domestic hygiene, and the germ theory, 1870-1900." Bulletin of the History of Medicine 64.4 (1990): 509-539. online; Tulchinsky, Theodore H., and Elena A. Varavikova. "A history of public health."
It lists activities tackling tuberculosis, malaria, acute risks of maternal and child mortality, including severe acute malnutrition, and other life-threatening diseases and health conditions.
World Tuberculosis Day, observed on 24 March each year, is designed to build public awareness about the global epidemic of tuberculosis (TB) and efforts to eliminate the disease. In 2018, 10 million people fell ill with TB, and 1.5 million died from the disease, mostly in low and middle-income countries .
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