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Fatty liver disease: Fatty liver disease (FLD) is essentially an inflammation of the liver. Although it can be caused by alcohol abuse, it is more often caused by obesity. ... Pale stools that are ...
Jaundice, also known as icterus, is a yellowish or greenish pigmentation of the skin and sclera due to high bilirubin levels. [3] [6] Jaundice in adults is typically a sign indicating the presence of underlying diseases involving abnormal heme metabolism, liver dysfunction, or biliary-tract obstruction. [7]
Macroscopically, the liver has a pale and spotty appearance in affected areas, as stasis of the blood causes pericentral hepatocytes (liver cells surrounding the central venule of the liver) to become deoxygenated compared to the relatively better-oxygenated periportal hepatocytes adjacent to the hepatic arterioles.
Acholia or hypocholia [1] is pallor of the feces, which lack their normal brown colour, as a result of impaired bile secretion into the bowel. [2] Acholia is a sign pointing to reduced or lacking flow of conjugated bilirubin into the bowel, as a result of a problem in the liver itself or in the biliary tree.
Patients with hyperbilirubinemia generally have poor outcome, particularly those with liver-dysfunction led jaundice. Drug-induced liver injury, as Hy's law states, patients with bilirubin of >3 mg/dL have 10% mortality rate. [36] End stage liver disease models also include hyperbilirubinemia as a critical parameter in prognosis of cirrhosis.
Steatorrhea refers to bulky, foul-smelling, oily stool that tends to be pale in color and float in the toilet bowl, resisting flushing. ... Genetic liver disease: Alagille syndrome is a genetic ...
Conjugated bilirubin passes from the liver into the intestines with bile. It's then excreted in stool. [citation needed] People with Gilbert syndrome have approximately 30 percent of normal bilirubin-UGT enzyme function, which contributes to a lower rate of glucuronidation of unconjugated bilirubin.
Signs and symptoms arising from liver damage in Alagille syndrome may include a yellowish tinge in the skin and the whites of the eyes (), itching (), pale stools (), an enlarged liver (hepatomegaly), an enlarged spleen (splenomegaly) and deposits of cholesterol in the skin (). [9]