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  2. Mixed connective tissue disease - Wikipedia

    en.wikipedia.org/.../Mixed_connective_tissue_disease

    The idea behind the "mixed" disease is that this specific autoantibody is also present in other autoimmune diseases such as systemic lupus erythematosus, polymyositis, scleroderma, etc. MCTD was characterized as an individual disease in 1972 by Sharp et al., [3] [4] and the term was introduced by Leroy [5] in 1980.

  3. Connective tissue disease - Wikipedia

    en.wikipedia.org/wiki/Connective_tissue_disease

    Connective tissue disease, also known as connective tissue disorder, or collagen vascular diseases, refers to any disorder that affects the connective tissue. [1] The body's structures are held together by connective tissues, consisting of two distinct proteins : elastin and collagen .

  4. Scleroderma - Wikipedia

    en.wikipedia.org/wiki/Scleroderma

    Eosinophilic fasciitis affects the connective tissue surrounding skeletal muscles, bones, blood vessels, and nerves in the arms and legs. Graft-versus-host disease is an autoimmune condition that occurs as a result of bone-marrow transplants in which the immune cells from the transplanted bone marrow attack the host's body.

  5. CREST syndrome - Wikipedia

    en.wikipedia.org/wiki/CREST_syndrome

    CREST is not easily diagnosed as it closely mimics symptoms of other connective tissue and autoimmune diseases. Diagnoses are usually given when a patient presents two or more of the five major clinical symptoms. [5] Additionally, blood exams can be given to test for a positive ANAs and ACAs or skin biopsies can be given to help confirm a ...

  6. Undifferentiated connective tissue disease - Wikipedia

    en.wikipedia.org/wiki/Undifferentiated...

    Undifferentiated connective tissue disease (UCTD) (also known as latent lupus or incomplete lupus [1]) is a disease in which the connective tissues are targeted by the immune system. It is a serological and clinical manifestation of an autoimmune disease .

  7. Overlap syndrome - Wikipedia

    en.wikipedia.org/wiki/Overlap_syndrome

    Examples of overlap syndromes in rheumatology include mixed connective tissue disease and scleromyositis. Diagnosis depends on which diseases the patient shows symptoms and has positive antibodies for in their lab serology. In overlap syndrome, features of the following diseases are found (most common listed): [1] Systemic lupus erythematosus (SLE)

  8. Thermo Fisher's (TMO) Autoimmune Disease Test Gets FDA Nod - AOL

    www.aol.com/news/thermo-fishers-tmo-autoimmune...

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  9. Systemic scleroderma - Wikipedia

    en.wikipedia.org/wiki/Systemic_scleroderma

    Systemic scleroderma, or systemic sclerosis, is an autoimmune rheumatic disease characterised by excessive production and accumulation of collagen, called fibrosis, in the skin and internal organs and by injuries to small arteries.