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Croup (/ k r uː p / KROOP), also known as croupy cough, is a type of respiratory infection that is usually caused by a virus. [2] The infection leads to swelling inside the trachea, which interferes with normal breathing and produces the classic symptoms of "barking/brassy" cough, inspiratory stridor and a hoarse voice. [2]
Clark's rule is a medical term referring to a mathematical formula used to calculate the proper dosage of medicine for children aged 2–17 based on the weight of the patient and the appropriate adult dose. [1] The formula was named after Cecil Belfield Clarke (1894–1970), a Barbadian physician who practiced throughout the UK, the West Indies ...
Prednisolone has a relatively short half-life, ranging 2–4 hours. It also has a large therapeutic window, considering the dosage required to produce a therapeutic effect is a few times higher than what the body naturally produces. [14] Prednisolone is 70–90% plasma protein bound, it binds to proteins such as albumin. [14]
Systemic glucocorticoids, such as oral prednisolone and intravenous hydrocortisone, are indicated for moderate to severe asthma exacerbation to reduce airway inflammation. [2] It is important for patients with refractory asthma exacerbation who are already on intensive bronchodilator therapy as airflow resistance in the airway is likely to be ...
Prednisolone sodium phosphate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester. References. External links "Prednisolone sodium phosphate ...
Children taking this drug may develop bone marrow suppression and an increased susceptibility to infections. [ 65 ] Cyclophosphamide is used at 500 mg per dose for 6 doses every 2 weeks over a one-month period or six 500 to 750 mg intravenous doses per square meter of body surface for 3 years to treat severe cSLE disease and as induction ...