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  2. Glomerular filtration rate - Wikipedia

    en.wikipedia.org/wiki/Glomerular_filtration_rate

    Glomerular filtration rate (GFR) is the volume of fluid filtered from the renal (kidney) glomerular capillaries into the Bowman's capsule per unit time. [4] Central to the physiologic maintenance of GFR is the differential basal tone of the afferent (input) and efferent (output) arterioles (see diagram).

  3. Glomerulus (kidney) - Wikipedia

    en.wikipedia.org/wiki/Glomerulus_(kidney)

    The glomerulus and its surrounding Bowman's capsule constitute a renal corpuscle, the basic filtration unit of the kidney. [2] The rate at which blood is filtered through all of the glomeruli, and thus the measure of the overall kidney function, is the glomerular filtration rate.

  4. Renal physiology - Wikipedia

    en.wikipedia.org/wiki/Renal_physiology

    Volume of blood plasma delivered to the kidney per unit time. PAH clearance is a renal analysis method used to provide an estimate. Approximately 625 ml/min. renal blood flow = (HCT is hematocrit) Volume of blood delivered to the kidney per unit time. In humans, the kidneys together receive roughly 20% of cardiac output, amounting to 1 L/min in ...

  5. Kidney - Wikipedia

    en.wikipedia.org/wiki/Kidney

    Filtration occurs in the glomerulus: one-fifth of the blood volume that enters the kidneys is filtered. Examples of substances reabsorbed are solute-free water, sodium, bicarbonate, glucose, and amino acids. Examples of substances secreted are hydrogen, ammonium, potassium and uric acid. The nephron is the structural and functional unit of the ...

  6. Filtration coefficient - Wikipedia

    en.wikipedia.org/wiki/Filtration_coefficient

    Typical units of Kf are mL/min/mmHg. The rate of filtration across the membrane is, by definition, the product of Kf and the net filtration pressure across the membrane. [1] [2] [3] Kf is frequently applied to the glomerular capillaries, which filter water into Bowman's capsule to form urine. Typically, in an adult human, the net filtration ...

  7. Nephron - Wikipedia

    en.wikipedia.org/wiki/Nephron

    The nephron is the functional unit of the kidney. [3] This means that each separate nephron is where the main work of the kidney is performed. A nephron is made of two parts: a renal corpuscle, which is the initial filtering component, and; a renal tubule that processes and carries away the filtered fluid. [4]: 1024

  8. Mammalian kidney - Wikipedia

    en.wikipedia.org/wiki/Mammalian_kidney

    The processes of blood plasma filtration, tubular reabsorption and tubular secretion occur in the kidneys, and urine formation is a result of these processes. [8] The kidneys produce renin [32] and erythropoietin [33] hormones, and are involved in the conversion of vitamin D to its active form. [34]

  9. Urinary system - Wikipedia

    en.wikipedia.org/wiki/Urinary_system

    The first step in urine formation is the filtration of blood in the kidneys. In a healthy human, the kidney receives between 12 and 30% of cardiac output, but it averages about 20% or about 1.25 L/min. The basic structural and functional unit of the kidney is the nephron.