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Monocytosis is an increase in the number of monocytes circulating in the blood. [1] Monocytes are white blood cells that give rise to macrophages and dendritic cells in the immune system. In humans, monocytosis occurs when there is a sustained rise in monocyte counts greater than 800/mm 3 to 1000/mm 3 .
Furthermore, anti-histone antibodies can also be positive in drug-induced lupus. [citation needed] Anti-Histone antibodies are positive in up to 95% of patients with drug induced lupus. The most common medications associated with drug induced lupus are hydralazine, procainamide, isoniazid, methyldopa, chlorpromazine, quinidine, and minocycline. [9]
Leukocytosis can be subcategorized by the type of white blood cell that is increased in number. Leukocytosis in which neutrophils are elevated is neutrophilia; leukocytosis in which lymphocyte count is elevated is lymphocytosis; leukocytosis in which monocyte count is elevated is monocytosis; and leukocytosis in which eosinophil count is elevated is eosinophilia.
Titres are monitored more often in cases of more active lupus than that of less active lupus at intervals of 1–3 months and 6–12 months, respectively. [1] Anti-dsDNA antibodies are highly associated with glomerulonephritis in SLE, although some patients with high titers of anti-dsDNA antibodies do not develop renal disease. This is most ...
An estimated 5 million people worldwide have some form of lupus disease. [23] 70% of lupus cases diagnosed are systemic lupus erythematosus. [23] 20% of people with lupus will have a parent or sibling who already has lupus or may develop lupus. [23] about 5% of the children born to individuals with lupus will develop the illness. [23]
16409 Ensembl ENSG00000169896 ENSMUSG00000030786 UniProt P11215 P05555 RefSeq (mRNA) NM_000632 NM_001145808 NM_001082960 NM_008401 RefSeq (protein) NP_000623 NP_001139280 n/a Location (UCSC) Chr 16: 31.26 – 31.33 Mb Chr 7: 127.66 – 127.72 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Integrin alpha M (ITGAM) is one protein subunit that forms heterodimeric integrin alpha-M beta ...
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