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The Purkinje fibers are further specialized to rapidly conduct impulses (having numerous fast voltage-gated sodium channels and mitochondria, and fewer myofibrils, than the surrounding muscle tissue). Purkinje fibers take up stain differently from the surrounding muscle cells because of having relatively fewer myofibrils than other cardiac cells.
Parallel fibers pass orthogonally through the Purkinje neuron's dendritic arbor, with up to 200,000 parallel fibers [6] forming a Granule-cell-Purkinje-cell synapse with a single Purkinje cell. Each adult Purkinje cell receives approximately 500 climbing fiber synapses, all originating from a single climbing fiber from the inferior olive. [ 7 ]
The bundle of His (BH) [1]: 58 or His bundle (HB) [1]: 232 (/ h ɪ s / "hiss" [2]) is a collection of heart muscle cells specialized for electrical conduction.As part of the electrical conduction system of the heart, it transmits the electrical impulses from the atrioventricular node (located between the atria and the ventricles) to the point of the apex of the fascicular branches via the ...
Purkinje fiber cell Smooth muscle cell (various types) iris: Myoepithelial cell: exocrine glands: Erythrocyte (red blood cell) erythroblasts Blood and immune system cells Megakaryocyte: Platelets if considered distinct cells, currently there's debate on the subject. Monocyte (white blood cell) Connective tissue macrophage (various types ...
The target for each climbing fiber is a specific neuron in the cerebellum referred to as a Purkinje Cell. During development, there are multiple climbing fibers on a purkinje cell, however these are pruned off during postnatal development, thus leaving a mature purkinje cell with a single climbing fiber. There are three major components of the ...
One exception is that fibers from the flocculonodular lobe synapse directly on vestibular nuclei without first passing through the deep cerebellar nuclei. The vestibular nuclei in the brainstem are analogous structures to the deep nuclei, since they receive both mossy fiber and Purkinje cell inputs.
The funny current is highly expressed in spontaneously active cardiac regions, such as the sinoatrial node (SAN, the natural pacemaker region), the atrioventricular node (AVN) and the Purkinje fibres of conduction tissue. The funny current is a mixed sodium–potassium current that activates upon hyperpolarization at voltages in the diastolic ...
Purkinje fibers, located in the heart; The visual Purkinje effect of how human beings do not see color in dim light; Purkinje images, reflections of objects from the surface of the cornea, and from the anterior and posterior surfaces of the lens; Purkinje Incorporated, a company that develops healthcare information technology software and services