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The Purkinje fibers are further specialized to rapidly conduct impulses (having numerous fast voltage-gated sodium channels and mitochondria, and fewer myofibrils, than the surrounding muscle tissue). Purkinje fibers take up stain differently from the surrounding muscle cells because of having relatively fewer myofibrils than other cardiac cells.
Parallel fibers pass orthogonally through the Purkinje neuron's dendritic arbor, with up to 200,000 parallel fibers [6] forming a Granule-cell-Purkinje-cell synapse with a single Purkinje cell. Each adult Purkinje cell receives approximately 500 climbing fiber synapses, all originating from a single climbing fiber from the inferior olive. [ 7 ]
Muscle cells are grouped into muscle fascicles by enveloping perimysium connective tissue. [1] Fascicles are bundled together by epimysium connective tissue. [1] Muscle fascicles typically only contain one type of muscle cell (either type I fibres or type II fibres), but can contain a mixture of both types.
Purkinje fiber cell Smooth muscle cell (various types) iris: Myoepithelial cell: exocrine glands: Erythrocyte (red blood cell) erythroblasts Blood and immune system cells Megakaryocyte: Platelets if considered distinct cells, currently there's debate on the subject. Monocyte (white blood cell) Connective tissue macrophage (various types ...
One exception is that fibers from the flocculonodular lobe synapse directly on vestibular nuclei without first passing through the deep cerebellar nuclei. The vestibular nuclei in the brainstem are analogous structures to the deep nuclei, since they receive both mossy fiber and Purkinje cell inputs.
Purkinje fibers, located in the heart; The visual Purkinje effect of how human beings do not see color in dim light; Purkinje images, reflections of objects from the surface of the cornea, and from the anterior and posterior surfaces of the lens; Purkinje Incorporated, a company that develops healthcare information technology software and services
Sensory information relayed from the pons through the mossy fibers to the granule cells is then sent along the parallel fibers to the Purkinje cells for processing. Extensive branching in white matter and synapses to granular cells ensures that input from a single mossy fiber axon will influence processing in a very large number of Purkinje cells.
Early in development, Purkinje cells are innervated by multiple climbing fibers, but as the cerebellum matures, these inputs gradually become eliminated resulting in a single climbing fiber input per Purkinje cell. These fibers provide very powerful, excitatory input to the cerebellum which results in the generation of complex spike excitatory ...