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Bromine is a chemical element; it has symbol Br and atomic number 35. ... Doses of 0.5 to 1 gram per day of bromide can lead to bromism. Historically, the therapeutic ...
Doses of 0.5 to 1 gram per day of bromide can lead to bromism. Historically, the therapeutic dose of bromide is about 3 to 5 grams of bromide, thus explaining why chronic toxicity (bromism) was once so common.
A biological role for bromine in humans has not been proven, but some organisms contain organobromine compounds. Humans typically consume 1 to 20 milligrams of bromine per day. There are typically 5 parts per million of bromine in human blood, 7 parts per million of bromine in human bones, and 7 parts per million of bromine in human tissue.
The study notes that the reference dose for decaBDE is 7,000 nanograms per kilogram of body weight a day; the reference dose for a 60-kilogram (132-pound) adult, it calculated, would be 42,000 ...
Theobromine is also suspected to induce right atrial cardiomyopathy after long term exposure at levels equivalent to approximately 15 g/kg (0.24 oz/lb) of dark chocolate per day. [13] According to the Merck Veterinary Manual , baker's chocolate of approximately 1.3 g/kg (0.021 oz/lb) of a dog's body weight is sufficient to cause symptoms of ...
At doses of 0.8–1.5 g/day (50–100 g cocoa), sweating, trembling and severe headaches were noted, with limited mood effects found at 250 mg/day. [ 34 ] Also, chocolate may be a factor for heartburn in some people because theobromine may affect the esophageal sphincter muscle in a way that permits stomach acids to enter the esophagus .
“There is now a large body of evidence that shows the optimal range for an active healthy adult is anywhere between 1.6g and 2.5g of protein per kilogram of body mass each day,” says Mather.
Since 2007, all US bromine has been produced by two companies in southern Arkansas, which extract bromine from brine pumped from the Smackover Formation. At an advertised price of US$3.50 to US$3.90 per kg, the US 2013 US production would have a value of roughly US$800 million.