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Autoimmune autonomic ganglionopathy is a type of immune-mediated autonomic failure that is associated with antibodies against the ganglionic nicotinic acetylcholine receptor present in sympathetic, parasympathetic, and enteric ganglia. Typical symptoms include gastrointestinal dysmotility, orthostatic hypotension, and tonic pupils. [1]
A number of conditions can feature dysautonomia, such as Parkinson's disease, multiple system atrophy, dementia with Lewy bodies, [6] Ehlers–Danlos syndromes, [7] autoimmune autonomic ganglionopathy and autonomic neuropathy, [8] HIV/AIDS, [9] mitochondrial cytopathy, [10] pure autonomic failure, autism, and postural orthostatic tachycardia ...
Autoimmune autonomic ganglionopathy; Autoimmune disease in women; Autoimmune urticaria; List of autoimmune diseases; Autoimmune encephalitis; Autoimmune enteropathy; Autoimmune gastrointestinal dysmotility; Autoimmune GFAP astrocytopathy; Autoimmune hemolytic anemia; Autoimmune hypophysitis; Autoimmune inner ear disease; Autoimmune oophoritis ...
An abnormal attack by the immune system (autoimmune autonomic ganglionopathy), sometimes as part of a paraneoplastic syndrome which can occur even when cancer has not yet been diagnosed. Certain infectious diseases. Some viruses and bacteria, such as botulism, Lyme disease and HIV, can cause autonomic neuropathy. Inherited disorders.
Sensory neuronopathy is thought to involve 40% of neuropathies in Sjogren's syndrome and 5% of all cases of Sjogren's overall, it is usually subacute in onset. Other immune mediated causes of sensory neuronopathy include systemic lupus erythematosus, autoimmune hepatitis and celiac disease. [4] Toxin exposure can also lead to sensory ...
Limb–girdle myasthenia gravis is a distinct condition from myasthenia gravis. It is an adult-onset, autoimmune condition affecting the neuromuscular junction. However, it lacks eye abnormalities and is associated with autoimmune conditions such as systemic lupus erythematosus, Hashimoto's thyroiditis, and thymoma. [81]
[23] [3] It is classified as a sensory ganglionopathy due to involvement of these ganglia. [ 61 ] [ b ] In electrodiagnostic testing , it has characteristic non-length-dependent abnormalities of sensory action potentials that occur globally, rather than distally decreasing sensory nerve action potential amplitudes. [ 57 ]
Complex regional pain syndrome (CRPS type 1 and type 2), sometimes referred to by the hyponyms reflex sympathetic dystrophy (RSD) or reflex neurovascular dystrophy (RND), is a rare and severe form of neuroinflammatory and dysautonomic disorder causing chronic pain, neurovascular, and neuropathic symptoms.