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[1] [2] CUSP9 is a treatment specifically targeted to glioblastoma that adds to a traditional cancer cell killing drug, temozolomide, nine older, non-cytotoxic drugs to block growth factors that enhance or drive glioblastoma growth — aprepitant blocks NK-1, auranofin inhibits thioredoxin reductase, captopril inhibits angiotensin converting ...
Despite aggressive treatments, GBM eventually recurs in most patients. Treatment at this point is similar, with surgery as indicated, as well as radiation treatment (unless the patient has already ...
The Glioblastoma Foundation funds research on discovering new and more effective treatments for glioblastoma patients. Grants are allocated to clinicians and scientists affiliated with institutions including Johns Hopkins Hospital, MD Anderson Cancer Center, and Columbia University.
Asunercept (INN; development codes APG101 and CAN008) [1] is a soluble CD95-Fc fusion protein which is in clinical development for the treatment of glioblastoma multiforme (GBM) and myelodysplastic syndromes (MDS). [2] Asunercept has been granted orphan drug status for the treatment of GBM and MDS in the EU and the US.
Optune was approved by the FDA for newly diagnosed glioblastoma on Oct. 5, 2015, [31] as a result of randomized phase 3 trial results that reported a 3-month advantage in overall survival and progression-free survival when added to chemotherapy with temozolomide. [23] [24] In the US, Medicare covers treatment, as of February 2020. [32]
The purpose of the ReSPECT-GBM Clinical Trial is to assess the safety, tolerability, and distribution of a new medication, Rhenium (186Re) Obisbemeda, in adults with recurrent glioblastoma after standard surgical, radiation, and/or chemotherapy treatment. ReSPECT-GBM is supported by the U.S. National Institutes of Health / National Cancer ...
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