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The tubercle bacteria many enter the abdomen via the consumption of infected milk. Those with existing pulmonary tuberculosis can have abdominal tuberculosis through the ingestion of infected sputum. [2] When the gastrointestinal tract is infected with the bacteria, epitheloid tubercles are formed in the lymphoid tissue of the submucosal layer.
Several endoscopic findings have been reported, including solitary ulcers, thickened gastric folds, mass lesions and nodules. As there may be infiltration of the submucosa, larger biopsy forceps, endoscopic ultrasound guided biopsy, endoscopic submucosal resection, or laparotomy may be required to obtain tissue.
The submucosa (or tela submucosa) is a thin layer of tissue in various organs of the gastrointestinal, respiratory, and genitourinary tracts. It is the layer of dense irregular connective tissue that supports the mucosa (mucous membrane) and joins it to the muscular layer, the bulk of overlying smooth muscle (fibers running circularly within layer of longitudinal muscle).
Peptic ulcers caused by NSAIDs differ from those caused by H. pylori as the latter's appear as a consequence of inflammation of the mucosa (presence of neutrophil and submucosal edema), the former instead as a consequence of a direct damage of the NSAID molecule against COX enzymes, altering the hydrophobic state of the mucus, the permeability ...
Gastric varices are dilated submucosal veins in the lining of the stomach, which can be a life-threatening cause of bleeding in the upper gastrointestinal tract.They are most commonly found in patients with portal hypertension, or elevated pressure in the portal vein system, which may be a complication of cirrhosis.
For localized, resectable adult GISTs, if anatomically and physiologically feasible, surgery is the primary treatment of choice. [22]: 69 Surgery can be potentially curative, but watchful waiting may be considered in small tumors in carefully selected situations. [28] Post-surgical adjuvant treatment may be recommended. [29]
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