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2. Methylnaltrexone - Wikipedia

   en.wikipedia.org/wiki/Methylnaltrexone

   Methylnaltrexone (MNTX, brand name Relistor), used in form of methylnaltrexone bromide (INN, USAN, BAN), is a medication that acts as a peripherally acting μ-opioid receptor antagonist that acts to reverse some of the side effects of opioid drugs such as constipation without significantly affecting pain relief or precipitating withdrawals.

3. Naloxegol - Wikipedia

   en.wikipedia.org/wiki/Naloxegol

   Naloxegol (INN; PEGylated naloxol; [4] trade names Movantik and Moventig) is a peripherally acting μ-opioid receptor antagonist developed by AstraZeneca, licensed from Nektar Therapeutics, for the treatment of opioid-induced constipation. [5] It was approved in 2014 in adult patients with chronic, non-cancer pain. [6]

4. Peripherally acting μ-opioid receptor antagonist - Wikipedia

   en.wikipedia.org/wiki/Peripherally_acting_μ...

   That can result in hard and dry stool and constipation for some patients. [2] OIC is one of the most common adverse effects caused by opioids, so the discovery of PAMORAs can prevent the effects that often compromise pain management. [3] Methylnaltrexone bromide was the first medication in the drug class approved by the FDA. [4]

5. Salix and Progenics Announce FDA Advisory Committee to ... - AOL

   www.aol.com/2013/06/11/salix-and-progenics...

   Salix and Progenics Announce FDA Advisory Committee to Review Relistor sNDA for Opioid-Induced Constipation in Patients with Chronic Pain RALEIGH, N.C. & TARRYTOWN, N.Y.--(BUSINESS WIRE)-- Salix ...

6. Salix and Progenics Announce FDA Advisory Committee ... - AOL

   www.aol.com/2013/10/01/salix-and-progenics...

   Salix and Progenics Announce FDA Advisory Committee Scheduled to Review Relistor sNDA for Opioid-Induced Constipation in Patients with Chronic Pain March 10-11, 2014 Meeting Date RALEIGH, N.C ...

7. Should You Be Taking a Fiber Supplement If You Can't Poop ...

   www.aol.com/lifestyle/taking-fiber-supplement...

   Constipation is no fun. Yet, it’s incredibly common. According to the National Institute of Diabetes and Digestive and Kidney Diseases, roughly 16% of U.S. adults struggle with it. And if you ...