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Nystatin is commonly used in treatment of lesions of the mouth caused by oral candidiasis. The drug can be formulated in pastilles or suspensions and is directly applied to the affected area. After application, patients should avoid taking food or drink for an hour to allow sufficient time for the drug to exert its effect locally. Oral ...
Antifungal resistance to drugs in the azole class tends to occur gradually over the course of prolonged drug therapy, resulting in clinical failure in immunocompromised patients (e.g., patients with advanced HIV receiving treatment for thrush or esophageal Candida infection). [15]
Some fungi (e.g. Candida krusei and fluconazole) exhibit intrinsic resistance to certain antifungal drugs or classes, whereas some species develop antifungal resistance to external pressures. Antifungal resistance is a One Health concern, driven by multiple extrinsic factors, including extensive fungicidal use, overuse of clinical antifungals ...
Drugs and drug candidates in this class are fungicidal against some yeasts (most species of Candida, but not Cryptococcus, Trichosporon, and Rhodotorula).Echinocandins also have displayed activity against Candida biofilms, especially in synergistic activity with amphotericin B and additive activity with fluconazole.
Nystatin, sold under the brand name Mycostatin among others, is an antifungal medication. [1] It is used to treat Candida infections of the skin including diaper rash, thrush, esophageal candidiasis, and vaginal yeast infections. [1] It may also be used to prevent candidiasis in those who are at high risk. [1]
Ketoconazole, sold under the brand name Nizoral, among others, is an antiandrogen, antifungal, and antiglucocorticoid medication used to treat a number of fungal infections. [11] Applied to the skin it is used for fungal skin infections such as tinea, cutaneous candidiasis, pityriasis versicolor, dandruff, and seborrheic dermatitis. [12]
Amphotericin B is an antifungal medication used for serious fungal infections and leishmaniasis. [3] The fungal infections it is used to treat include mucormycosis, aspergillosis, blastomycosis, candidiasis, coccidioidomycosis, and cryptococcosis. [4]
Ibrexafungerp, sold under the brand name Brexafemme, is an antifungal medication used to treat vulvovaginal candidiasis (VVC) (vaginal yeast infection). [1] It is taken orally (by mouth). [1] It is also currently undergoing clinical trials for other indications via an intravenous (IV) formulation. An estimated 75% of women will have at least ...