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Steatosis (retention of lipid) and onset of steatohepatitis may represent successive stages in FLD progression. [23] Liver disease with extensive inflammation and a high degree of steatosis often progresses to more severe forms of the disease. [24] Hepatocyte ballooning and necrosis of varying degrees are often present at this stage.
Steatohepatitis is a type of fatty liver disease, characterized by inflammation of the liver with concurrent fat accumulation in liver. Mere deposition of fat in the liver is termed steatosis , and together these constitute fatty liver changes.
Steatosis, also called fatty change, is abnormal retention of fat within a cell or organ. [1] Steatosis most often affects the liver – the primary organ of lipid metabolism – where the condition is commonly referred to as fatty liver disease. Steatosis can also occur in other organs, including the kidneys, heart, and muscle. [2]
Nonalcoholic steatohepatitis (NASH). With this type of fatty liver disease, you’ll have fat in your liver, inflammation, and liver cell damage. This can lead to cirrhosis (liver scarring) and ...
Metabolic dysfunction–associated steatotic liver disease (MASLD), previously known as non-alcoholic fatty liver disease (NAFLD), [a] is a type of chronic liver disease.This condition is diagnosed when there is excessive fat build-up in the liver (hepatic steatosis), and at least one metabolic risk factor.
Steatohepatitis is seen in both alcoholic and non-alcoholic liver disease and is the culmination of a cascade of events that began with injury. In the case of non-alcoholic steatohepatitis, this cascade is initiated by changes in metabolism associated with obesity, insulin resistance, and lipid dysregulation.
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