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A colorectal polyp is a polyp (fleshy growth) occurring on the lining of the colon or rectum. [1] Untreated colorectal polyps can develop into colorectal cancer. [2] Colorectal polyps are often classified by their behaviour (i.e. benign vs. malignant) or cause (e.g. as a consequence of inflammatory bowel disease).
One’s biological age, which measures the body’s physiological state, may help predict who is at risk for developing colon polyps, a known risk factor for colorectal cancer.
The incidence of the mutation is between 1 in 10,000 and 1 in 15,000 births. By age 35 years, 95% of individuals with FAP (>100 adenomas) have polyps. Without colectomy, colon cancer is virtually inevitable. The mean age of colon cancer in untreated individuals is 39 years (range 34–43 years). [13]
The colorectal adenoma is a benign glandular tumor of the colon and the rectum. It is a precursor lesion of the colorectal adenocarcinoma ( colon cancer ). [ 1 ] [ 2 ] [ 3 ] They often manifest as colorectal polyps .
This can result in the formation of colon polyps, which the Mayo Clinic defines as small clumps of cells that form on the lining of the colon. ... Colon cancer could become the leading cause of ...
Colorectal cancer is now one of the leading causes of cancer deaths in men and women under 50 years old. ... personal history of colon polyps or cancer, inflammatory bowel disease, family history ...
Gardner's syndrome (also known as Gardner syndrome, familial polyposis of the colon, [1] or familial colorectal polyposis [2]) is a subtype of familial adenomatous polyposis (FAP). Gardner syndrome is an autosomal dominant form of polyposis characterized by the presence of multiple polyps in the colon together with tumors outside the colon. [ 3 ]
Some of the inherited genetic disorders that can cause colorectal cancer include familial adenomatous polyposis and hereditary non-polyposis colon cancer; however, these represent less than 5% of cases. [2] [3] It typically starts as a benign tumor, often in the form of a polyp, which over time becomes cancerous. [2]